Preclinical R&D Expert – In-house Drug Development

About the Role

Are you a preclinical R&D scientist who has taken drug programs from the bench toward the clinic — and curious how AI is reshaping drug discovery? Our client is a venture-backed AI lab building frontier AI platforms and physics-based foundation models for chemistry, materials science, and drug discovery. They want hands-on experts across drug modalities to help guide what they build.

In this role, you'll:

• Review technical materials and real-world R&D data in your area of expertise
• Label, classify, and annotate scientific data and model outputs to improve model performance
• Provide expert perspective on key scientific and development decisions (target/modality selection, optimization, trade-offs, risk)
• Help define structure and quality standards for the client's dataset pipeline
• Participate in expert discussions, interviews, and research engagements

You're a strong fit if you:

• Have hands-on, non-administrative preclinical R&D experience at a company that develops its own drug assets in-house and has taken programs to the clinic — Must Have
• Work in a core R&D function: discovery biology, medicinal chemistry, protein/antibody engineering, computational, in vivo/translational, pharmacology/PK-PD, toxicology, or CMC/formulation — Must Have
• Have hands-on experience with one or more drug modalities (small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, radioligand therapies, etc.)
• 5+ years of relevant industry R&D experience (flexible based on depth)
• Have taken a program through lead optimization or IND-enabling/preclinical development (nice to have)
• Have experience at mid-sized, emerging, or resource-constrained biotech — ideally currently outside the top-20 pharmaceutical companies (nice to have)

This is a hands-on preclinical R&D role — likely not the right fit if your work is mainly CRO/CDMO services, academic-only, QC/analytical-only, clinical-development-only, diagnostics, or regulatory/medical-writing.

Role details:

• You'll interface directly with the client team
• Remote · hourly · seniority welcome from individual contributor through Director

We consider all qualified applicants without regard to legally protected characteristics and provide reasonable accommodations upon request.

Contract and Payment Terms

• You will be engaged as an independent contractor.
• This is a fully remote role that can be completed on your own schedule.
• Projects can be extended, shortened, or concluded early depending on needs and performance.
• Your work at Mercor will not involve access to confidential or proprietary information from any employer, client, or institution.
• Payments are weekly on Stripe or Wise based on services rendered.
• Please note: We are unable to support H1-B or STEM OPT candidates at this time.

About Mercor

Mercor partners with leading AI labs and enterprises to train frontier models using human expertise. You will work on projects that focus on training and enhancing AI systems. You will be paid competitively, collaborate with leading researchers, and help shape the next generation of AI systems in your area of expertise.